Witek, Rafal: search on Z-Library

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1

Role for hedgehog pathway in regulating growth and function of invariant NKT cells

Wing-Kin Syn, Rafal P. Witek, Stuart M. Curbishley, Youngmi Jung, Steve S. Choi, Barbara Enrich, Alessia Omenetti, Kolade M. Agboola, Caitlin M. Fearing, Herbert Tilg, David H. Adams, Anna Mae Diehl

Journal:

European Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 445 KB

english, 2009

2

Ex Vivo transduced liver progenitor cells as a platform for gene therapy in mice

Sihong Song, Rafal P. Witek, Yuanqing Lu, Young-Kook Choi, Donghang Zheng, Marda Jorgensen, Chengwen Li, Terence R. Flotte, Byron E. Petersen

Journal:

Year:

2004

Language:

english

File:

PDF, 825 KB

english, 2004

3

Repair-related activation of hedgehog signaling promotes cholangiocyte chemokine production

Alessia Omenetti, Wing-Kin Syn, Youngmi Jung, Heather Francis, Alessandro Porrello, Rafal P. Witek, Steve S. Choi, Liu Yang, Marlyn J. Mayo, M. Eric Gershwin, Gianfranco Alpini, Anna Mae Diehl

Journal:

Year:

2009

Language:

english

File:

PDF, 620 KB

english, 2009

4

Pan-caspase inhibitor VX-166 reduces fibrosis in an animal model of nonalcoholic steatohepatitis

Rafal P. Witek, W. Carl Stone, F. Gamze Karaca, Wing-Kin Syn, Thiago A. Pereira, Kolade M. Agboola, Alessia Omenetti, Youngmi Jung, Vanessa Teaberry, Steve S. Choi, Cynthia D. Guy, John Pollard, Peter

Journal:

Year:

2009

Language:

english

File:

PDF, 2.57 MB

english, 2009

5

Accumulation of natural killer T cells in progressive nonalcoholic fatty liver disease

Wing-Kin Syn, Ye Htun Oo, Thiago A. Pereira, Gamze F. Karaca, Youngmi Jung, Alessia Omenetti, Rafal P. Witek, Steve S. Choi, Cynthia D. Guy, Caitlin M. Fearing, Vanessa Teaberry, Fausto E.L. Pereira,

Journal:

Year:

2010

Language:

english

File:

PDF, 2.31 MB

english, 2010

6

Activation of Rac1 promotes hedgehog-mediated acquisition of the myofibroblastic phenotype in rat and human hepatic stellate cells

Steve S. Choi, Rafal P. Witek, Liu Yang, Alessia Omenetti, Wing-Kin Syn, Cynthia A. Moylan, Youngmi Jung, Gamze F. Karaca, Vanessa S. Teaberry, Thiago A. Pereira, Jiangbo Wang, Xiu-Rong Ren, Anna Mae

Journal:

Year:

2010

Language:

english

File:

PDF, 1.58 MB

english, 2010

7

Ethics and patentability in biotechnology

Journal:

Science and Engineering Ethics

Year:

2005

Language:

english

File:

PDF, 177 KB

english, 2005

8

TRENDS IN THE EVOLUTION OF THE EUGLENID PELLICLE

Brian S. Leander, Rafal P. Witek, Mark A. Farmer

Journal:

Year:

2001

Language:

english

File:

PDF, 3.27 MB

english, 2001

9

Genetic differences in oxidative stress and inflammatory responses to diet-induced obesity do not alter liver fibrosis in mice

Wing-Kin Syn, Liu Yang, Dian Jung Chiang, Yue Qian, Youngmi Jung, Gamze Karaca, Steve S. Choi, Rafal P. Witek, Alessia Omenetti, Thiago A. Pereira, Anna Mae Diehl

Journal:

Liver International

Year:

2009

Language:

english

File:

PDF, 886 KB

english, 2009

10

Somatostatin stimulates the migration of hepatic oval cells in the injured rat liver

Youngmi Jung, Seh-Hoon Oh, Rafal P. Witek, Bryon E. Petersen

Journal:

Liver International

Year:

2012

Language:

english

File:

PDF, 688 KB

english, 2012

11

Viral factors induce Hedgehog pathway activation in humans with viral hepatitis, cirrhosis, and hepatocellular carcinoma

Pereira, Thiago de Almeida, Witek, Rafal P, Syn, Wing-Kin, Choi, Steve S, Bradrick, Shelton, Karaca, Gamze F, Agboola, Kolade M, Jung, Youngmi, Omenetti, Alessia, Moylan, Cynthia A

Journal:

Laboratory Investigation

Year:

2010

Language:

english

File:

PDF, 1.43 MB

english, 2010

12

A potential role of somatostatin and its receptor SSTR4 in the migration of hepatic oval cells

Jung, Youngmi, Oh, Seh-Hoon, Zheng, Donghang, Shupe, Thomas D, Witek, Rafal P, Petersen, Bryon E

Journal:

Laboratory Investigation

Year:

2006

Language:

english

File:

PDF, 783 KB

english, 2006

13

Fate-Mapping Evidence That Hepatic Stellate Cells Are Epithelial Progenitors in Adult Mouse Livers

Liu Yang, Youngmi Jung, Alessia Omenetti, Rafal P. Witek, Steve Choi, Hendrika M. Vandongen, Jiawen Huang, Gianfranco D. Alpini, Anna Mae Diehl

Journal:

Year:

2008

Language:

english

File:

PDF, 3.47 MB

english, 2008

14

Organotypic liver culture models: Meeting current challenges in toxicity testing

LeCluyse, Edward L., Witek, Rafal P., Andersen, Melvin E., Powers, Mark J.

Journal:

Critical Reviews in Toxicology

Year:

2012

Language:

english

File:

PDF, 2.18 MB

english, 2012

15

Evaluation of an in vitro toxicogenetic mouse model for hepatotoxicity

Stephanie M. Martinez, Blair U. Bradford, Valerie Y. Soldatow, Oksana Kosyk, Amelia Sandot, Rafal Witek, Robert Kaiser, Todd Stewart, Kirsten Amaral, Kimberly Freeman, Chris Black, Edward L. LeCluyse,

Journal:

Toxicology and Applied Pharmacology

Year:

2010

Language:

english

File:

PDF, 1.25 MB

english, 2010

16

Coexpression index of estrogen receptor alpha mRNA isoforms in simple, complex hyperplasia without atypia, complex atypical hyperplasia and adenocarcinoma

Andrzej Witek, Monika Paul-Samojedny, Rafał Stojko, Bohdan Seifert, Urszula Mazurek

Journal:

Gynecologic Oncology

Year:

2007

Language:

english

File:

PDF, 446 KB

english, 2007

17

Recombinant adenoviruses expressing Steatosis-associated Hepatitis C virus genotype 3 Core protein produce intracellular lipid accumulation in cultured and primary hepatocytes

Guan Qiang, Liu Yang, Rafal P. Witek, Ravi Jhaveri

Journal:

Year:

2009

Language:

english

File:

PDF, 1.88 MB

english, 2009

18

Bone Marrow–Derived Hepatic Oval Cells Differentiate Into Hepatocytes in 2-Acetylaminofluorene/Partial Hepatectomy–Induced Liver Regeneration

Seh–Hoon Oh, Rafal P. Witek, Si–Hyun Bae, Donghang Zheng, Youngmi Jung, Anna C. Piscaglia, Bryon E. Petersen

Journal:

Gastroenterology

Year:

2007

Language:

english

File:

PDF, 5.25 MB

english, 2007

19

Accumulation of Hedgehog-Responsive Progenitors Parallels Alcoholic Liver Disease Severity in Mice and Humans

Youngmi Jung, Kevin D. Brown, Rafal P. Witek, Alessia Omenetti, Liu Yang, Margon Vandongen, Richard J. Milton, Ian N. Hines, Richard A. Rippe, Laurent Spahr, Laura Rubbia–Brandt, Anna Mae Diehl

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 5.44 MB

english, 2008

20

Liver Cell–Derived Microparticles Activate Hedgehog Signaling and Alter Gene Expression in Hepatic Endothelial Cells

Rafal P. Witek, Liu Yang, Renshui Liu, Youngmi Jung, Alessia Omenetti, Wing–Kin Syn, Steve S. Choi, Yeiwon Cheong, Caitlin M. Fearing, Kolade M. Agboola, Wei Chen, Anna Mae Diehl

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 3.59 MB

english, 2009

21

Hedgehog-Mediated Epithelial-to-Mesenchymal Transition and Fibrogenic Repair in Nonalcoholic Fatty Liver Disease

Wing–Kin Syn, Youngmi Jung, Alessia Omenetti, Manal Abdelmalek, Cynthia D. Guy, Liu Yang, Jiangbo Wang, Rafal P. Witek, Caitlin M. Fearing, Thiago A. Pereira, Vanessa Teaberry, Steve S. Choi, J. Conde

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 4.32 MB

english, 2009

22

Macrophage-derived hedgehog ligands promotes fibrogenic and angiogenic responses in human schistosomiasis mansoni

Pereira, Thiago A., Xie, Guanhua, Choi, Steve S., Syn, Wing-Kin, Voieta, Izabela, Lu, Jiuyi, Chan, Isaac S., Swiderska, Marzena, Amaral, Kirsten B., Antunes, Carlos M., Secor, William E., Witek, Rafal

Journal:

Year:

2013

Language:

english

File:

PDF, 1.20 MB

english, 2013

23

Identification of Liver Cancer-Specific Aptamers Using Whole Live Cells

Shangguan, Dihua, Meng, Ling, Cao, Zehui Charles, Xiao, Zeyu, Fang, Xiaohong, Li, Ying, Cardona, Diana, Witek, Rafal P., Liu, Chen, Tan, Weihong

Journal:

Analytical Chemistry

Year:

2008

Language:

english

File:

PDF, 722 KB

english, 2008

24

S1926 Increased Short-Term Risk for Liver-Related Mortality Parallels Accumulation of Hedgehog-Responsive Progenitors in Patients with Alcoholic Steatohepatitis

Jung, Youngmi, Brown, Kevin D., Witek, Rafal P., Omenetti, Alessia, Yang, Liu, Vandongen, Hendrika, Milton, Richard J., Hines, Ian, Rippe, Richard A., Spahr, Laurent, Rubbia-Brandt, Laura, Diehl, Anna

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 117 KB

english, 2008

25

T1616 Pan-Caspase Inhibitor VX-166 Reduces Fibrosis in An Animal Model of Non-Alcoholic Steatohepatitis

Witek, Rafal P., Stone, Walter C., Karaca, Gamze F., Pollard, John, Charlton, Peter, Diehl, Anna Mae

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 48 KB

english, 2009

26

343 Myofibroblasts Promote the Growth of Biliary Tree During Cholestatic Liver Injury By Suppressing Tryptophan Hydroxylase 2 (TPH2) Expression and Serotonin Secretion in Neighboring Cholangiocytes

Omenetti, Alessia, Yang, Liu, Gainetdinov, Raul R., Choi, Steve S., Witek, Rafal P., Jung, Youngmi, Syn, Wing-Kin, Chen, Wei, Caron, Marc G., Diehl, Anna Mae

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 51 KB

english, 2009

27

89 Sustained Activation of RAC1 Enhances Hedgehog-Mediated Epithelial-Mesenchymal Transition in Mice with Chronic Liver Injury

Choi, Steve S., Witek, Rafal P., Omenetti, Alessia, Yang, Liu, Syn, Wing-Kin, Jung, Youngmi, Sicklick, Jason K., Diehl, Anna Mae

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 51 KB

english, 2009

28

1 Specific Inhibition of Ikkβ in Hepatocytes Induces Proliferation of Liver Progenitors in Injured Livers

Jung, Youngmi, Witek, Rafal P., Syn, Wing-Kin, Choi, Steve S., Omenetti, Alessia, Diehl, Anna Mae

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 50 KB

english, 2009

29

685 Glial Fibrillary Acidic Protein(+) Progenitors Regenerate Adult Livers

Yang, Liu, Jung, Youngmi, Huang, Jiawen, Omenetti, Alessia, Witek, Rafal P., Choi, Steve S., Alpini, Gianfranco, Diehl, Anna Mae

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 84 KB

english, 2008

30

M1577 Culture Activation of Murine Hepatic Stellate Cells Involves Hedgehog Pathway Activation and Epithelial-to-Mesenchymal Transitions

Choi, Steve S., Omenetti, Alessia, Yang, Liu, Witek, Rafal P., Brown, Kevin D., Vazquez-Chantada, Mercedes, Huang, Jiawen, Jung, Youngmi, Syn, Wing-Kin, Sicklick, Jason K., Diehl, Anna Mae

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 72 KB

english, 2008

31

T1821 Liver-Derived Microparticles Carry Biologically-Active Hedgehog Morphogens in Blood and Bile

Witek, Rafal P., Liu, Renshui, Yang, Liu, Jung, Youngmi, Brown, Kevin, Omenetti, Alessia, Vazquez-Chantada, Mercedes, Syn, Wing-Kin, Choi, Steve S., Huang, Jiawen, Chen, Wei, Diehl, Anna Mae

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 68 KB

english, 2008

32

S1585 Myofibroblast-Derived Soluble Factors Upregulate Chemokine Gene Expression in Neighboring Cholangiocytes

Omenetti, Alessia, Porrello, Alessandro, Syn, Wing-Kin, Choi, Steve S., Jung, Youngmi, Yang, Liu, Brown, Kevin D., Witek, Rafal P., Vandongen, Hendrika, Diehl, Anna Mae

Journal:

Gastroenterology

Year:

2008

Language:

english

File:

PDF, 61 KB

english, 2008

33

Detection of Transketolase in Bone Marrow–Derived Insulin-Producing Cells: Benfotiamine Enhances Insulin Synthesis and Glucose Metabolism

Oh, Seh-Hoon, Witek, Rafal P., Bae, Si-Hyun, Darwiche, Houda, Jung, Youngmi, Pi, Liya, Brown, Alicia, Petersen, Bryon E.

Journal:

Stem Cells and Development

Year:

2009

Language:

english

File:

PDF, 432 KB

english, 2009

34

Towards novel 5-HT7 versus 5-HT1A receptor ligands among LCAPs with cyclic amino acid amide fragments: Design, synthesis, and antidepressant properties. Part II

Canale, Vittorio, Kurczab, Rafał, Partyka, Anna, Satała, Grzegorz, Witek, Jagna, Jastrzębska-Więsek, Magdalena, Pawłowski, Maciej, Bojarski, Andrzej J., Wesołowska, Anna, Zajdel, Paweł

Journal:

European Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.47 MB

english, 2015

35

Multi-Step Protocol for Automatic Evaluation of Docking Results Based on Machine Learning Methods—A Case Study of Serotonin Receptors 5-HT 6 and 5-HT 7

Smusz, Sabina, Mordalski, Stefan, Witek, Jagna, Rataj, Krzysztof, Kafel, Rafał, Bojarski, Andrzej J.

Journal:

Journal of Chemical Information and Modeling

Year:

2015

Language:

english

File:

PDF, 577 KB

english, 2015

36

Effect of menopause on salivary glands and oral mucosa

Srebrzyńska-Witek, Agnieszka, Koszowski, Rafał

Journal:

Menopausal Review

Year:

2013

Language:

polish

File:

PDF, 92 KB

polish, 2013

37

TRENDS IN THE EVOLUTION OF THE EUGLENID PELLICLE

Leander, Brian S., Witek, Rafal P., Farmer, Mark A.

Journal:

Year:

2001

Language:

english

File:

PDF, 3.28 MB

english, 2001

38

Ex Vivo Transduction and Transplantation of Bone Marrow Cells for Liver Gene Delivery of α1-Antitrypsin

Li, Hong, Lu, Yuanqing, Witek, Rafal P, Chang, Lung-Ji, Campbell-Thompson, Martha, Jorgensen, Marda, Petersen, Bryon, Song, Sihong

Journal:

Molecular Therapy

Year:

2010

Language:

english

File:

PDF, 713 KB

english, 2010

39

Trends in the Evolution of the Euglenid Pellicle

Brian S. Leander, Rafal P. Witek and Mark A. Farmer

Journal:

Year:

2001

Language:

english

File:

PDF, 5.67 MB

english, 2001

40

Differential Effects of Trovafloxacin on TNF-α and IL-6 Profiles in a Rat Hepatocyte–Kupffer Cell Coculture System

Bonzo, Jessica A., Rose, Kelly, Freeman, Kimberly, Deibert, Erica, Amaral, Kirsten B., Ferguson, Stephen S., Andersen, Melvin E., Witek, Rafal P., LeCluyse, Edward L.

Journal:

Applied In Vitro Toxicology

Year:

2015

Language:

english

File:

PDF, 1.13 MB

english, 2015

41

Monocrotaline, an Alternative to Retrorsine-Based Hepatocyte Transplantation in Rodents

Witek, Rafal P., Fisher, Samantha H., Petersen, Bryon E.

Journal:

Cell Transplantation

Year:

2005

Language:

english

File:

PDF, 208 KB

english, 2005

42

Relationship between anterior mandibular bone thickness and the angulation of incisors and canines—a CBCT study

Srebrzyńska-Witek, Agnieszka, Koszowski, Rafał, Różyło-Kalinowska, Ingrid

Journal:

Clinical Oral Investigations

Year:

2017

Language:

english

File:

PDF, 2.85 MB

english, 2017

43

Dispersion-corrected DFT struggles with predicting three-body interaction energies

Jankiewicz, Wojciech, Podeszwa, Rafal, Witek, Henryk A.

Journal:

Journal of Chemical Theory and Computation

Year:

2018

Language:

english

File:

PDF, 920 KB

english, 2018

44

Perspective on In Vitro Liver Toxicity Models

Witek, Rafal P., Bonzo, Jessica A.

Journal:

Applied In Vitro Toxicology

Year:

2018

Language:

english

File:

PDF, 63 KB

english, 2018

45

The development of a hairless phenotype in barley roots treated with gold nanoparticles is accompanied by changes in the symplasmic communication

Milewska-Hendel, Anna, Witek, Weronika, Rypień, Aleksandra, Zubko, Maciej, Baranski, Rafal, Stróż, Danuta, Kurczyńska, Ewa U.

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 3.86 MB

english, 2019

46

Evaluation of pooled human hepatocytes to assess the induction potential of new chemical entities

Simmermacher, Jean, Jarres, Russell A., Tarabelsi, Lucien, Bray, Wendy J., Witek, Rafal P., Sane, Ramola, Sinz, Michael, Soars, Matthew

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2018

Language:

english

File:

PDF, 54 KB

english, 2018

47

Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans

Omenetti, Alessia, Porrello, Alessandro, Jung, Youngmi, Yang, Liu, Popov, Yury, Choi, Steve S., Witek, Rafal P., Alpini, Gianfranco, Venter, Juliet, Vandongen, Hendrika M., Syn, Wing-Kin, Baroni, Gian

Journal:

Journal of Clinical Investigation

Year:

2008

Language:

english

File:

PDF, 1.26 MB

english, 2008